Case reports

Beckwith-Wiedemann syndrome associated with congenital cytomegalovirus in an HIV-exposed neonate

K E Sprong, C A Wright, M Mabenge, S Govender

Abstract


Congenital cytomegalovirus (CMV) infection is associated with preterm birth and congenital abnormalities, which could be exacerbated by maternal co-infection with HIV. This case report describes an HIV-exposed neonate with Beckwith-Wiedemann syndrome (BWS), born by a mother who had a CMV infection of the placenta, who demised following laparoscopic repair of an omphalocele.


Authors' affiliations

K E Sprong, Department of Biochemistry and Microbiology, Nelson Mandela University, Port Elizabeth, South Africa

C A Wright, Lancet Laboratories, Johannesburg, South Africa; Division of Anatomical Pathology, Department of Pathology, University of Stellenbosch, Cape Town, South Africa

M Mabenge, Department of Obstetrics and Gynaecology, Dora Nginza Hospital, Walter Sisulu University, Port Elizabeth, South Africa

S Govender, Department of Biochemistry and Microbiology, Nelson Mandela University, Port Elizabeth, South Africa

Full Text

PDF (1274KB)

Keywords

Cytomegalovirus, preterm birth, Human Immunodeficiency Virus, Beckwith-Wiedemann Syndrome, placenta

Cite this article

South African Journal of Obstetrics and Gynaecology 2020;26(2):79-81. DOI:10.7196/sajog.1595

Article History

Date submitted: 2020-06-16
Date published: 2020-12-15

Article Views

Abstract views: 802
Full text views: 39

Comments on this article

*Read our policy for posting comments here