Research

Gestational outcomes of patients with multiple sclerosis: A tertiary centre experience

O Ozyuncu, A Tanacan, F Aktoz, M Buyukeren, R Karabudak, M S Beksac

Abstract


Background. Multiple sclerosis (MS) is a disease that predominantly affects the young female population. It is important for an obstetrician to know the effects of pregnancy on MS, and vice versa.

Objective. To demonstrate the impact of MS on pregnancy outcomes. Methods. We retrospectively evaluated demographic features, clinical characteristics, and obstetric outcomes of 47 pregnancies in 24 patients with MS, between January 2007 and December 2016.

Results. Patients were divided into three groups: (i) 35 pregnancies in patients with MS who were in remission at the beginning of pregnancy; (ii) 10 pregnancies in patients with MS whose disease was exacerbated at the beginning of pregnancy; and (iii) 2 pregnancies in patients with active MS whose symptoms were relieved after becoming pregnant. The overall early pregnancy loss rate was 36.2%, whereas it was 60% and 31.4% in the exacerbation and remission groups, respectively; and the overall preterm delivery rate was 30%, while it was 29.1% and 50% in the remission and exacerbation groups, respectively.

Conclusion. Miscarriage and preterm delivery seem to be significant obstetric complications in pregnant women with MS.


Authors' affiliations

O Ozyuncu, Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

A Tanacan, Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

F Aktoz, Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

M Buyukeren, Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey

R Karabudak, Department of Neurology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

M S Beksac, Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

Full Text

PDF (112KB)

Keywords

Pregnancy, Multiple Sclerosis, Antenatal Care

Cite this article

South African Journal of Obstetrics and Gynaecology 2018;24(3):79-82. DOI:10.7196/sajog.1368

Article History

Date submitted: 2018-06-28
Date published: 2019-02-22

Article Views

Abstract views: 2773
Full text views: 995

Comments on this article

*Read our policy for posting comments here


The South African Medical Association is the official publisher of the SAJOG.

                                                           

                                        SOUTH AFRICAN MEDICAL ASSOCIATION

                                                         Events | Careers | CPD

 

The South African Journal of Obstetrics and Gynaecology| Online ISSN: 2305-8862 | Print ISSN: 0038-2329 | 

Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0) | 

This journal is protected by a Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0) | Read our privacy policy.

SAMA Journals: South African Medical Journal African Journal of Health Professions Education South African Journal of Bioethics and Law South African Journal of Child Health | Southern African Journal of Critical Care  | South African Journal of Obstetrics and Gynaecology | Undergraduate Research in Health African Journal of Thoracic and Critical Care Medicine  | Southern African Journal of Public Health