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The impact of uterine artery embolisation on fibroid volume at 43.6 months in women with symptomatic fibroids at a tertiary-level hospital

R T Mogakane, Z Abdool, S Ahmad, H M Swanepoel

Abstract


Background. Symptomatic uterine fibroids have a significant impact on women’s health. Surgical intervention (myomectomy and hysterectomy) has been the mainstay of treatment. Women living with symptomatic uterine fibroids contribute significantly to a growing waiting list for surgery in South African public hospitals. Uterine artery embolisation (UAE) is a newer treatment option and has shown to be a minimally invasive, safe and effective alternative to surgery for such women. 

Objective. To evaluate the efficacy of UAE in women with symptomatic fibroid uterus. 

Methods. A prospective, observational, single-centre study of 51 women with symptomatic fibroid uterus who underwent UAE at Steve Biko Academic Hospital from February 2007 to November 2012. 

Results. A total of 51 women underwent UAE, 3 of whom were lost to follow-up. The remaining 48 women were followed for a mean duration of 43.6 months. There was a statistically significant reduction in the mean uterine and dominant myoma volumes, as well as improvement in the haemoglobin levels (p=0.001). The mean uterine and dominant fibroid volume reductions were 38% and 58%, respectively. Minor complications were reported in 19% of the women (fever, post-embolisation syndrome and vaginal fibroid passage were frequently reported complications). Reintervention (hysterectomy and gonadotropin-releasing hormone analogue use) was required in 35% of women. 

Conclusion. UAE has a good clinical effect on fibroid volume reduction. It is a treatment option that can be considered prior to major surgery in a select group of women with symptomatic fibroid uterus.


Authors' affiliations

R T Mogakane, Department of Obstetrics and Gynaecology, Steve Biko Academic Hospital, Faculty of Health Sciences, University of Pretoria, South Africa

Z Abdool, Department of Obstetrics and Gynaecology, Steve Biko Academic Hospital, Faculty of Health Sciences, University of Pretoria, South Africa

S Ahmad, Department of Radiology, Steve Biko Academic Hospital, Faculty of Health Sciences, University of Pretoria, South Africa

H M Swanepoel, Department of Radiology, Steve Biko Academic Hospital, Faculty of Health Sciences, University of Pretoria, South Africa

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Keywords

Fibroid uterus; Leiomyomas; uterine artery embolization

Cite this article

South African Journal of Obstetrics and Gynaecology 2017;23(3):97-100. DOI:10.7196/sajog.1228

Article History

Date submitted: 2017-07-11
Date published: 2017-12-22

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